Description
Product Overview
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Active Ingredient: Lactulose 3.35 g per 5 ml
A synthetic, non-absorbable disaccharide composed of fructose and galactose -
Formulation: Oral syrup, typically supplied in a 100 ml amber bottle with a measuring cup
Mechanism & Uses
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Mechanism of Action: Lactulose is broken down by colonic bacteria into acids, increasing osmotic pressure in the colon, drawing in water, and softening stool; it also acidifies the colon to convert ammonia into ammonium, aiding in its elimination
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Indications:
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Constipation (chronic and habitual)
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Hepatic encephalopathy, for reducing blood ammonia levels and managing neurological symptoms associated with liver disease
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Dosage & Administration
| Condition | Dose |
|---|---|
| Constipation (Adults) | Initially 15 ml twice daily, adjust as needed |
| Children | Under 1 yr: 2.5 ml twice daily |
Hepatic Encephalopathy| 30–50 ml, three times daily, adjusted to produce 2–3 soft stools daily
Safety & Precautions
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Side Effects: Initial bloating, gas, and cramps are common and usually transient. Overdose may result in diarrhea.
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Precautions: Use cautiously in patients with lactose intolerance or diabetes
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Pregnancy & Lactation: Category B—generally considered safe in pregnancy; caution advised during lactation
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Overdose: No known reports; expect diarrhea and cramps if it occurs
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