Description
What It Is
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Active Ingredient: Povidone-iodine 10% w/v (equal to approximately 1% free iodine), a potent broad-spectrum antiseptic
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Marketed under the Betadine brand, globally recognized for reliable infection control.
Key Uses
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Skin antisepsis before and after surgical and minor procedures (e.g., injections).
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Wound care: cleanses cuts, scrapes, burns, and abrasions to reduce infection risk.
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Often used in pre- and post-operative preparation and degerming of mucous membranes
How to Use
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Topical application only—not for ingestion or use in eyes/nose .
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Apply full strength to clean, dry skin; avoid pooling in folds. Rinse off before covering with dressings if needed
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For routine wound care, apply gently once or twice daily depending on injury severity.
Mechanism of Action
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Povidone-iodine works by releasing free iodine, which penetrates microbial cells and destroys essential proteins, RNA, and DNA—offering fast and effective antimicrobial action. Effective against bacteria, fungi, viruses, protozoa, and spores
Safety, Side Effects & Precautions
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Common side effects: mild skin irritation, redness, or burning. Discontinue if irritation persists
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Systemic risk if used extensively or on large wounds—can affect thyroid function, especially in vulnerable populations (e.g., thyroid disease, lithium therapy)
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Avoid use in:
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Individuals with iodine or PVP sensitivities
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Thyroid disorders or lithium therapy
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Neonates or prolonged use over large areas
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Storage & Misc
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Store in a cool, dry place below 30 °C, out of children’s reach.
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Available OTC and included in WHO’s List of Essential Medicines
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