Ambolyt 100 ml Syrup

Description

Active Ingredient

• Ambroxol Hydrochloride – 15 mg per 5 ml of syrup

Classification

• Belongs to the cough expectorants & mucolytics therapeutic class

Indications

Used for treating productive coughs and various respiratory tract conditions accompanied by thick, sticky mucus, including:

• Acute and chronic bronchitis

• Laryngitis, pharyngitis, sinusitis, rhinitis

• Asthmatic bronchitis or asthma with heavy expectoration

• Bronchiectasis, chronic pneumonia, and other similar inflammatory disorders

Mechanism of Action

• Ambroxol, a metabolite of bromhexine, promotes breakdown of mucoproteins and mucopolysaccharide fibers, reducing mucus viscosity and aiding expectoration.

• It stimulates surfactant (phospholipid) production by alveolar cells to lower surface tension and enhance airway clearance.

• It also exhibits anti-inflammatory, antioxidant, and bronchial hyperactivity–reducing effects, improving airway patency in conditions like COPD

Dosage & Administration

Preferably taken after meals.

• Children (Syrup formulation):

  • 2–5 years: 2.5 ml (½ tsp), 2–3 times/day

  • 5–10 years: 5 ml (1 tsp), 2–3 times/day

  • 10 years and adults: 10 ml (2 tsp), 3 times/day

• Pediatric Drops Alternative:

  • 0–6 months: 0.5 ml twice daily

  • 6–12 months: 1 ml twice daily

  • 1–2 years: 1.25 ml twice daily.

Contraindications & Interactions

• Should not be used by individuals with known hypersensitivity to ambroxol or bromhexine

• Avoid concomitant use with antitussive agents like codeine, which may inhibit expectoration of liquefied mucus

Side Effects

• Common: mild gastrointestinal discomfort, epigastric pain, feeling of gastric fullness

• Rare: allergic reactions including skin rash, urticaria (hives), and angioneurotic edema

Pregnancy & Lactation

• Animal studies show no teratogenic effects, but use during the first trimester is discouraged, and safety during lactation is not established

Precautions & Warnings

• Use with caution in patients with:

  • Gastric or duodenal ulcers

  • Convulsive disorders

  • Hepatic or renal insufficiency

Storage

• Store in a dry place, away from direct light, at temperatures not exceeding 30 °C. Keep out of reach of children