Hactosec Syrup 150 ml

Description

Active Ingredient & Formulation

Hactosec contains levodropropizine, a peripherally acting antitussive that suppresses dry, non-productive cough by modulating sensory pathways in the respiratory tract, without central nervous system effects like sedation or respiratory depression.

Each milliliter delivers 6 mg levodropropizine (equivalent to 30 mg per 5 ml). The syrup is clear, colorless, and comes in a 150 ml glass bottle with a dosing spoon and box packaging.

Indications & Mechanism of Action

Used for symptomatic relief of dry or irritating coughs in both children (from age 2) and adults. It acts on peripheral afferent nerves, reducing cough reflex without affecting the central nervous system, offering a safer alternative to opioid-based treatments.

Clinical evidence—including a meta-analysis—demonstrates that levodropropizine is more effective than central antitussives (like codeine or dextromethorphan) in reducing cough frequency, intensity, and night awakenings.

Dosage & Administration

• Adults & children ≥ 12 years:

  • 10 ml (60 mg) three times daily, at least 6 hours apart.

• Children (by weight/body category):

  • 10–20 kg: 2–3 ml, up to three times daily.

  • 20–30 kg: 5 ml, three times daily.

  • >30 kg: 10 ml, three times daily.

  • Alternatively, 1–2 mg/kg per dose, up to 3× daily.

➡ Take the syrup away from meals. A plastic spoon included in the package is marked for 2 ml, 3 ml, and 5 ml measures.

Contraindications & Precautions

• Contraindicated in:

  • Children under 2 years of age.

  • Individuals with hypersensitivity to levodropropizine or excipients.

  • Pregnant or breastfeeding women.

  • Patients with severe liver impairment or certain respiratory conditions (e.g., Kartagener’s syndrome).

• Caution in:

  • Patients with liver or kidney failure.

  • Diabetics, since the syrup contains sucrose (0.5 g/ml).

  • Individuals with known allergies to preservatives (e.g., parabens).

• Avoid use with sedatives or mucolytic/expectorant agents due to potential interactions.

Side Effects

Most side effects are mild and transient:

• CNS: fatigue, drowsiness, dizziness.

• Gastrointestinal: nausea, vomiting, diarrhea, abdominal discomfort.

• Cardiovascular: palpitations, hypotension.

• Others: headaches, tremor, cough, allergic skin reactions.

Storage

Keep below 30 °C in its original packaging, protected from light, and out of reach of children. Do not use beyond expiry date.